Skin Rejuvenation with PRGF (Plasma Rich in Growth Factors): Detailed Guide

Skin rejuvenation treatment with PRGF (Plasma Rich in Growth Factors), also known as Platelet Rich Plasma (PRP), is one of the most advanced and natural regenerative medicine therapies. It consists of using the patient's own cells and growth factors to stimulate the regeneration of skin tissue, improving the quality, luminosity and firmness of the skin.

This procedure is highly valued in Spain for its autologous nature (material from the body itself is used), which guarantees maximum biocompatibility and eliminates the risk of rejection or allergies.

What is PRGF and How to Get It?

The PRGF is a concentrated part of the patient's blood that contains a high density of platelets, which are responsible for initiating the healing and cellular regeneration processes in the organism.

Detailed Obtaining Process (Protocol in Clinic):

Blood Extraction: The aesthetic doctor or nurse extracts a small sample of blood from the patient (similar to a routine blood analysis).
Centrifuge: The blood is placed in a specialized centrifuge machine. This machine rotates at high speed, separating blood components: red blood cells, white blood cells and plasma.
Isolation of PRGF: Isolate and extract the layer of plasma that contains the maximum concentration of platelets. This is Plasma Rich in Growth Factors (PRGF).
Activation: PRGF is activated through a solution of calcium chloride or a heat process (depending on the technique) so that the platelets release their growth factors.

Action Mechanism on the Floor:

Growth Factors act as cellular messengers, which, when injected into the skin, directly stimulate fibroblasts (cells that produce collagen and elastin). This results in an increase in cellular activity, promoting the creation of new support fibers and vascular tissue.

Detailed Benefits for Skin Rejuvenation

The PRGF offers a progressive and natural improvement in skin quality, without an immediate relleno effect.

Benefit Details of Regenerative Action Application Zones

Brightness and Revitalization Increase in microcirculation and cellular activity, which improves tone and the appearance of dull or fatigued skin. Rostro (general), Cuello y Escote.

Improves Texture and Firmness Stimulating collagen and elastin improves the thickness of the dermis, reducing light sagging and fine wrinkles progressively. Contorno de Ojos (patas de gallo), Mejillas, Flacidez del Cuello.

Scar Treatment The Growth Factors accelerate the skin repair processes, being very effective in improving the appearance of acne scars and some stretch marks. Atrophic scars and acne marks.

Internal Hydration Although it is not a volume replenishment, tissue regeneration improves the skin's capacity to retain water. Hand Rejuvenation (combined with rellenos) and Escote.

Protocol, Results and Security

Typical Protocol: To obtain optimal results, a cycle of 3 to 4 initial sessions is recommended, spaced every 3 to 4 weeks. Afterwards, maintenance sessions are suggested every 6 to 12 months.

Progressive Results: Results are not immediate. The patient begins to notice improvements in the texture and shine of the skin after 3 weeks, with an optimal and definitive result visible within 3 months of starting the cycle.

Safety (Minimum Risks): The PRGF is highly safe due to its autologous nature. The risks are limited to the injection itself:

Recovery (Downtime): Minimum. There may be slight redness, swelling or small bruises at injection points, which disappear within 24 to 48 hours.

Contraindications: It is crucial that the doctor evaluates the patient before treatment. It is contraindicated in cases of embarrassment, lactation, active autoimmune diseases or coagulation disorders.

Treatment with PRGF is the preferred option for those looking for natural and biological rejuvenation, using the body's own regenerative capacity to heal and improve the skin.