Bioidentical Hormones are 100% Natural because they come from Plants

Denied: This is the most persistent and confusing myth. Although it is certain that they originate from vegetable precursors (such as soybeans or wild names), they are not simply “natural” or a vegetable extract.

The Truth: These hormones must undergo a chemical synthesis process in a laboratory to transform the plant precursors into a molecular structure that is identical to that of human hormones. Therefore, they are medicines that have been manufactured, not raw extracts of plants. The “natural” label is misleading.

El Danger of the Myth: This belief could lead people to think that, besides being “natural”, they do not have risks, which is false.

Myth 2: Bioidentical Hormones are Safer and No Riesgos.

Denied: This is the most dangerous myth. The knowledge that it has a molecular structure identical to that of human hormones does not mean that it is free from risks.

The Truth: Bioidentical hormones are potent medicines that have significant effects on the body and, therefore, contain risks. The real safety of HRT depends on factors that are much more important than the “bioidentical” term:

Route of Administration: Transdermal estrogen (patches, gels) is safer for the heart than oral estrogen, although the hormone is bioidentical or synthetic, because it prevents the first pass through the liver.

Type of Progesterone: Natural micronized (bioidentical) progesterone has been associated with a more favorable safety profile for the risk of breast cancer than some synthetic progestins. This demonstrates that security is in the specific molecule, not in the general name.

Time of Initiation: The risk of cardiovascular complications is significantly lower if HRT begins in the “wind of opportunity” (before 60 years or in 10 years after the onset of menopause).

The Danger of the Myth: Believing that bioidentical hormones are “without risk” can lead people to avoid regular medical monitoring, which is essential for safe therapy.

Myth 3: Measures are Made for Each Person and the Dose is More Personalized.

Debunked: This myth confuses the reality of standardized bioidentical hormones with “computed” (non-regulated) formulations.

The Truth: The bioidentical hormones that are commonly prescribed in Spain (gels, patches, micronized progesterone tablets) are standardized medicines manufactured by pharmaceutical companies. Your dosis is necessary and the same for everyone. True personalization comes from the hand of the doctor, who selects the dosage and type of hormone most suitable for the symptoms and risk profile of each patient, but with a standardized and approved product.

El Matiz: There are “compuestas” preparations that are manufactured to order, but they are not regulated by the Spanish Agency of Medicines and Sanitary Products (AEMPS). Therefore, its safety, effectiveness and, above all, the consistency of the dosage in each batch are not guaranteed, which is a major medical concern.

Myth 4: I'm Exactly the Same as Synthetic Hormones, Just a Different Name.

Denied: Although both are medicines, this statement is incorrect.

The Truth: The difference in molecular structure is real and scientifically relevant. The idea that bioidentical hormones are identical to human hormones can impact how the body metabolizes them, and this process can be the least favorable in terms of secondary effects and risks. For example, micronized natural progesterone is not the same as medroxyprogesterone acetate (MPA).

El Matiz: The term “bioidentical” has real scientific support, but it should not be used to imply safety that does not exist. Both options have a place in medicine and their use must be justified by evidence.

Conclusion: An Informed Decision, not Based on Myths

Debunking these myths is essential so that we can make an informed and safe decision about hormone replacement therapy. The truth is that bioidentical hormones are a valid, effective and often preferred form of HRT, but they are not a risk-free “natural” solution.

The key to successful treatment is open and honest dialogue with your specialist doctor in Spain. It will guide you through scientific evidence, evaluate your unique risk factors, your symptoms and your preferences to design an individualized treatment plan, choosing the hormones that have been tested, regulated and that have the most suitable risk profile for use.

Disclaimer: The information provided in this document is for educational purposes and should not be considered as medical advice. Always consult a qualified health professional before making any decision about your treatment.